ABSTRACT
ABSTRACTSuture granuloma is a mass forming benign lesion that develops at the site of surgery as a foreign body reaction to non-absorbable suture material. We present a case of suture granuloma that developed at the inguinal region after orchiectomy, and define the sonography, color Doppler sonography and real-time ultrasound elastography findings in correlation with the histopathological findings.
Subject(s)
Adult , Humans , Male , Granuloma, Foreign-Body/etiology , Granuloma, Foreign-Body , Orchiectomy/adverse effects , Postoperative Complications , Sutures/adverse effects , Elasticity Imaging Techniques , Granuloma, Foreign-Body/pathology , Postoperative Complications/pathology , Ultrasonography, Doppler, ColorABSTRACT
Testicular calculus is an extremely rare case with unknown etiology and pathogenesis. To our knowledge, here we report the third case of testicular calculus. A 31-year-old man was admitted to our clinic with painful solid mass in left testis. After diagnostic work-up for a possible testicular tumour, he underwent inguinal orchiectomy and histopathologic examination showed a testicular calculus.
Solid testicular lesions in young adults generally correspond to testicular cancer. Differential diagnosis should be done carefully.
In young adults with painful and solid testicular mass with hyperechogenic appearance on scrotal ultrasonography, testicular calculus must be kept in mind in differential diagnosis. Further reports on this topic may let us do more clear recommendations about the etiology and treatment of this rare disease.
Subject(s)
Humans , Male , Adult , Testicular Diseases/pathology , Calculi/pathology , Rare Diseases/pathology , Testicular Diseases/surgery , Testicular Neoplasms/diagnosis , Calculi/surgery , Orchiectomy , Rare Diseases/surgery , Diagnosis, DifferentialABSTRACT
Introduction and Aim: To assess the impact of new alternative solutions to formaldehyde and xylene on tissue processing, 13 different tissue processings were designed and performed on thirteen different tissues by using fi ve different fi xatives (formaldehyde, Glyo-Fixx®, FineFix®, Cell-block®, Green- Fix®) and four different clearing agents (xylene, Sub-X®, Bio-clear®, Shandon Xylene Substitute®). Materials and Methods: Hematoxylin and Eosine stained sections were compared by using qualitative histomorphological criterions. Histochemical and immunohistochemical (IHC) staining results were compared with qualitative and quantitative data obtained by a computer program, respectively. Tissue sections were tested for the availability of chromogenic in situ hybridization, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) extraction, and DNA quality by polymerase chain reaction. Results: The quality of sections was well for all tissue processings. All alternative solutions were suitable for histochemistry. IHC staining results showed that alternative solutions that contain glyoxal as active agent need optimization for this application. The clearance of signals with chromogenic in situ hybridization were nearly same and well for all tissue samples. Furthermore, tissue processes that do not contain formaldehyde were found to be superior on preservation of nucleic acids. Conclusion: Formaldehyde-free fi xatives and alternative clearing agents have potential in routine pathology and research to replace formaldehyde and xylene.